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Stereotactic Functional Neurosurgery
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Month: December 2019

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  • 2019 Archives
  • Dec Archives

An erratum about the ancestral origin of Abu Al Husain Ibn Abdullah Ibn Sina. Khan ZH, Minagar M, Dehghan-Tezerjani M, Javadi SAH. World Neurosurg. 2019 Dec 18.

  • Posted by Marwan Hariz
  • Categories Publications
  • Comments 0 comment

SUMMARY: The authors describe Avicenna´s origin and some of his work, including on trepanation, hydrocephalus, vermis etc, insisting that he was Persian, born to Persia, with Persian roots, he spoke Persian (although his writings were in Arabic) and should be …

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Clinical trials for deep brain stimulation: Current state of affairs. Harmsen IE, Elias GJB, Beyn ME, Boutet A, Pancholi A, Germann J, Mansouri A, Lozano CS, Lozano AM. Brain Stimul. 2019 Nov 23.

  • Posted by Marwan Hariz
  • Categories Publications
  • Comments 0 comment

SUMMARY: The authors aimed to update on the state of DBS-related clinical human research by cataloging and summarizing clinical trials that have been completed or are currently ongoing in this field worldwide. They searched for clinical trials pertaining to DBS, …

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An Analysis of Clinical Outcome and Tractography following Bilateral Anterior Capsulotomy for Depression. Avecillas-Chasin JM, Hurwitz TA, Bogod NM, Honey CR. Stereotact Funct Neurosurg. 2019 Dec 20:1-12.

  • Posted by Marwan Hariz
  • Categories Publications
  • Comments 0 comment

SUMMARY: 10 patients received bilateral anterior capsulotomy (BAC) for depression. 6 patients were responders (≥50% improvement in BDI), 4 patients non-responders (< 50% improvement). Tractography revealed that in the responder group, there was less involvement of the DLPFC pathways than …

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The Suitability of Different Subtypes and Dimensions of Obsessive-Compulsive Disorder for Treatment with Anterior Capsulotomy: A Long-Term Follow-Up Study. Gong F, Li B, Zhang S, Wang Y, Gao Y, Xu Y, Wang X, Xiong B, Li D, Wen R, Qin Z, Wang W. Stereotact Funct Neurosurg. 2019 Nov 29:1-18.

  • Posted by Marwan Hariz
  • Categories Publications
  • Comments 0 comment

SUMMARY: The authors analysed outcome of 54 consecutive anterior capsulotomy (AC) up to 36 months after surgery, according to phenotype. They found that AC is generally effective in reducing symptoms of most subtypes of OCD. However, patients categorized into the …

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A prospective international multi-center study on safety and efficacy of deep brain stimulation for resistant obsessive-compulsive disorder. Menchón JM, Real E, Alonso P, Aparicio MA, Segalas C, Plans G, Luyten L, Brunfaut E, Matthijs L, Raymakers S, Bervoets C, Higueras A, Katati M, Guerrero J, Hurtado M, Prieto M, Stieglitz LH, Löffelholz G, Walther S, Pollo C, Zurowski B, Tronnier V, Kordon A, Gambini O, Ranieri R, Franzini A, Messina G, Radu-Djurfeldt D, Schechtmann G, Chen LL, Eitan R, Israel Z, Bergman H, Brelje T, Brionne TC, Conseil A, Gielen F, Schuepbach M, Nuttin B, Gabriëls L. Mol Psychiatry. 2019 Oct 29.

  • Posted by Marwan Hariz
  • Categories Publications
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SUMMARY: This is the famous Medtronic-sponsored European open labeled multicenter study on OCD DBS that took long long time to complete and even longer time to publish judging by the use of Kinetra stimulator in most of the patients. It …

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Long-Term Outcomes of Subcallosal Cingulate Deep Brain Stimulation for Treatment-Resistant Depression. Crowell AL, Riva-Posse P, Holtzheimer PE, Garlow SJ, Kelley ME, Gross RE, Denison L, Quinn S, Mayberg HS. Am J Psychiatry. 2019 Nov 1;176(11):949-956.

  • Posted by Marwan Hariz
  • Categories Publications
  • Comments 0 comment

SUMMARY: Here the authors examined participants enrolled in a previous (failed) clinical trial of Subcallosal cingulum (SCC) DBS for treatment-resistant depression. 28 patients receiving SCC DBS for 4–8 years showed that response and remission rates were maintained at >50% and …

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Long-term deep brain stimulation of the ventral anterior limb of the internal capsule for treatment-resistant depression. van der Wal JM, Bergfeld IO, Lok A, Mantione M, Figee M, Notten P, Beute G, Horst F, van den Munckhof P, Schuurman PR, Denys D. J Neurol Neurosurg Psychiatry. 2019 Dec 4.

  • Posted by Marwan Hariz
  • Categories Publications
  • Comments 0 comment

SUMMARY: The authors aimed to assess the efficacy and safety of DBS targeted at the ventral anterior limb of the internal capsule (vALIC) in 25 patients with treatment resistant depression (TRD) during a 1-year, open-label, maintenance period, which followed a …

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Is deep brain stimulation (DBS) a safe and effective treatment for adults with dystonia? – A Cochrane Review summary with commentary. Cecchi F. NeuroRehabilitation. 2019 Dec 18.

  • Posted by Marwan Hariz
  • Categories Publications
  • Comments 0 comment

SUMMARY The author assessed the effects of DBS in adults with dystonia by analyzing a Cochrane Review searching for RCTs with a parallel design, comparing DBS versus placebo, sham intervention, or best medical/surgical treatment. She found only 2 RCTs, “at …

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Tractography-based targeting of the ventral intermediate nucleus: accuracy and clinical utility in MRgFUS thalamotomy. Ranjan M, Elias GJB, Boutet A, Zhong J, Chu P, Germann J, Devenyi GA, Chakravarty MM, Fasano A, Hynynen K, Lipsman N, Hamani C, Kucharczyk W, Schwartz ML, Lozano AM, Hodaie M. J Neurosurg. 2019 Sep 27:1-8.

  • Posted by Marwan Hariz
  • Categories Publications
  • Comments 0 comment

SUMMARY: The authors wrote: “Tractography-based targeting of the thalamic ventral intermediate nucleus (T-VIM) is a novel method conferring patient-specific selection of VIM coordinates for tremor surgery; however, its accuracy and clinical utility in magnetic resonance imaging–guided focused ultrasound (MRgFUS) thalamotomy …

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Non-motor outcomes depend on location of neurostimulation in Parkinson’s disease. Petry-Schmelzer JN, Krause M, Dembek TA, Horn A, Evans J, Ashkan K, Rizos A, Silverdale M, Schumacher W, Sack C, Loehrer PA, Fink GR, Fonoff ET, Martinez-Martin P, Antonini A, Barbe MT, Visser-Vandewalle V, Ray-Chaudhuri K, Timmermann L, Dafsari HS; EUROPAR and the IPMDS Non-Motor PD Study Group. Brain. 2019 Nov 1;142(11):3592-3604.

  • Posted by Marwan Hariz
  • Categories Publications
  • Comments 0 comment

SUMMARY: Using VTAs and the Lead DBS toolbox to analyse the location of active contacts in 91 PD patients who were investigated with the so called non-motor scale, the authors concluded that “Marked improvements of mood/apathy were observed for neurostimulation …

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