SUMMARY: The authors describe Avicenna´s origin and some of his work, including on trepanation, hydrocephalus, vermis etc, insisting that he was Persian, born to Persia, with Persian roots, he spoke Persian (although his writings were in Arabic) and should be …
SUMMARY: The authors aimed to update on the state of DBS-related clinical human research by cataloging and summarizing clinical trials that have been completed or are currently ongoing in this field worldwide. They searched for clinical trials pertaining to DBS, …
SUMMARY: 10 patients received bilateral anterior capsulotomy (BAC) for depression. 6 patients were responders (≥50% improvement in BDI), 4 patients non-responders (< 50% improvement). Tractography revealed that in the responder group, there was less involvement of the DLPFC pathways than …
SUMMARY: The authors analysed outcome of 54 consecutive anterior capsulotomy (AC) up to 36 months after surgery, according to phenotype. They found that AC is generally effective in reducing symptoms of most subtypes of OCD. However, patients categorized into the …
SUMMARY: This is the famous Medtronic-sponsored European open labeled multicenter study on OCD DBS that took long long time to complete and even longer time to publish judging by the use of Kinetra stimulator in most of the patients. It …
SUMMARY: Here the authors examined participants enrolled in a previous (failed) clinical trial of Subcallosal cingulum (SCC) DBS for treatment-resistant depression. 28 patients receiving SCC DBS for 4–8 years showed that response and remission rates were maintained at >50% and …
SUMMARY: The authors aimed to assess the efficacy and safety of DBS targeted at the ventral anterior limb of the internal capsule (vALIC) in 25 patients with treatment resistant depression (TRD) during a 1-year, open-label, maintenance period, which followed a …
SUMMARY The author assessed the effects of DBS in adults with dystonia by analyzing a Cochrane Review searching for RCTs with a parallel design, comparing DBS versus placebo, sham intervention, or best medical/surgical treatment. She found only 2 RCTs, “at …
SUMMARY: The authors wrote: “Tractography-based targeting of the thalamic ventral intermediate nucleus (T-VIM) is a novel method conferring patient-specific selection of VIM coordinates for tremor surgery; however, its accuracy and clinical utility in magnetic resonance imaging–guided focused ultrasound (MRgFUS) thalamotomy …
SUMMARY: Using VTAs and the Lead DBS toolbox to analyse the location of active contacts in 91 PD patients who were investigated with the so called non-motor scale, the authors concluded that “Marked improvements of mood/apathy were observed for neurostimulation …