SUMMARY: In 12 patients with STN DBS who had a special IPG called “Activa PC + S” (that allows recording of LFP) the authors could record LFPs On and OFF med at 8 months after surgery showing that beta activity …
SUMMARY: This is a case of severe MRI visible massive peri-electrode edema on one side stretching down to the STN. This appeared only 4 days after surgery when the patient developed lethargy and mild confusion in absence of fever or …
SUMMARY: The authors retrospectively evaluated 43 patients with PD who received bilateral STN-DBS. The volumes of activated tissue were analyzed to obtain significant stimulation clusters predictive of 4 clinical outcomes: improvements in bradykinesia, rigidity, tremor, and reduction of dopaminergic medication. …
SUMMARY: EARLYSTIM has been very advertised since the paper published in NEJM in 2013. Kim et al argue that “despite of more benefit from DBS surgery than best medical therapy in early stage of PD, we need to consider the …
SUMMARY: The authors reviewed 58 articles to explore the similarities and differences between “awake” and “asleep” DBS techniques. The surgical procedures, clinical outcomes, costs and complications of each technique were compared in detail through literature review. The results demonstrated that …
SUMMARY: The authors describe a patient in whom STN DBS implantation based on one MER pass resulted in good response at 1 mA but sustained dysarthria at 2 mA, suggesting a slightly anteriorly located electrode. Instead of lead adjustment and …
Valldeoriola F, Muñoz E, Rumià J, Roldán P, Cámara A, Compta Y, Martí MJ, Tolosa E. Parkinsonism Relat Disord. 2019 Mar;60:153-157. SUMMARY: One of the most challenging and unresolved problems in PD is the treatment of patients with dopa resistant …
Matias CM, Frizon LA, Nagel SJ, Lobel DA, Machado AG. J Neurosurg. 2018 Dec 1;129(6):1572-1578. SUMMARY: 33 patients (27 with PD)) underwent implantation of 64 DBS leads under GA without MER. MRI was done immediately postop and fused to the …
The Dark Side of Globalization: Lack of Universal Levodopa Availability. Merello M. Mov Disord Clin Pract. 2018 Nov 16;6(1):7-8. AND “New and improved” DBS batteries? Kiss ZHT, Hariz M. Brain Stimul. 2019 Jul – Aug;12(4):833-834. AND Battery obsolescence, industry profit …
Jellison S, Roberts W, Bowers A, Combs T, Beaman J, Wayant C, Vassar M. BMJ Evid Based Med. 2019 Aug 5.[Epub ahead of print] SUMMARY: The authors identified ‘spin’ in abstracts of randomised controlled trials (RCTs) with nonsignificant primary endpoints …