SUMMARY: Psychiatric neurosurgery has resurfaced over the past two decades. Little is known, however, about current public opinions, expectations, hopes, and concerns over this evolution in neurotechnology, particularly given the controversial history of psychosurgery. To fill this knowledge gap, we …
SUMMARY: Retrospective study comparing results obtained from DBS in the Voi-Cm/Pf (41 patients) and antero-medial Globus Pallidus internus (am-GPi) (14 patients), over a period of 48 months, showing a stable improvement in the YGTSS and YBOCS in both groups (p …
SUMMARY In OCD DBS, multiple targets have been investigated. OBJECTIVE: To systematically review the current level and quality of evidence supporting OCD-DBS by target region with the goal of establishing a common nomenclature. 28 articles were included for review. Articles …
SUMMARY: Eight randomized controlled trials (RCTs) (n = 85) and 38 observational studies (case reports and case series) (n = 225) were included. In RCTs, mean differences between sham and active stimulation in Y-BOCS and Hamilton Depression Rating Scale (HDRS) …
SUMMARY: 19 OCD patients with DTN DBS evaluated at 24 months using YBOCS and GAF. At a 24-month mean YBOCS score improved by 53.4% from 33.3±3.5 to 15.8±9.1. 14 out of 19 patients were considered as responders, 5 out of …
SUMMARY: Gamma ventral capsulotomy (GVC) in 21 patients with OCD. Mean follow-up 60.7 months. YBOCS 35.7 decreased to 15.3 at 36 months follow-up. 15 patients (75%) achieved a full response. Of those patients, 7 (35%) were considered to be in …
SUMMARY: More than 80 OCD DBS patients since 2005: guiding principles for optimizing DBS stimulation parameters in OCD. Adjustments in stimulation parameters are performed in a fixed order. First, electrode contact activation is determined by the position of the electrodes …
SUMMARY:21 patients with PD submitted to STN DBS compared with 19 eligible surgery candidates. Clinical measures included Hoehn and Yahr scale, UPDRS III, PDQ39, Becks Depressive inventory, and sexual function evaluation (Female Sexual Function Index and International Index of Erectile …
SUMMARY: Double-blind, sham-controlled, randomized multicenter (23 centers) trial STN DBS using BSc electrodes. 160 Patients were randomly assigned to receive either active therapeutic stimulation settings (active group) or subtherapeutic stimulation settings (control group) for the 3-month blinded period. The primary …
SUMMARY: To assess the prevalence and the cumulative incidence of dementia at short-, medium- and long-term (1, 5, and 10 years) follow-up after STN DBS and to evaluate potential risk factors for postoperative dementia. A total of 175 patients were …