SUMMARY: The authors aimed to assess the efficacy and safety of DBS targeted at the ventral anterior limb of the internal capsule (vALIC) in 25 patients with treatment resistant depression (TRD) during a 1-year, open-label, maintenance period, which followed a …
SUMMARY The author assessed the effects of DBS in adults with dystonia by analyzing a Cochrane Review searching for RCTs with a parallel design, comparing DBS versus placebo, sham intervention, or best medical/surgical treatment. She found only 2 RCTs, “at …
SUMMARY: The authors wrote: “Tractography-based targeting of the thalamic ventral intermediate nucleus (T-VIM) is a novel method conferring patient-specific selection of VIM coordinates for tremor surgery; however, its accuracy and clinical utility in magnetic resonance imaging–guided focused ultrasound (MRgFUS) thalamotomy …
SUMMARY: Using VTAs and the Lead DBS toolbox to analyse the location of active contacts in 91 PD patients who were investigated with the so called non-motor scale, the authors concluded that “Marked improvements of mood/apathy were observed for neurostimulation …
SUMMARY: 14 patients with a mean postoperative follow-up of 40.6 ± 30 months. DBS ended the dystonic storm in 87.5% of cases (7/8), while pallidotomy had a success rate of 83.3% (5/6). No significant differences were observed between the two …
SUMMARY: The authors investigated 26 consecutive ET patients who received DBS in cZi using a comprehensive neuropsychological test battery covering the major cognitive domains preop. and 12 months postop. There were no major adverse effects on patient performance on the …
SUMMARY: A 16 year old girl with severe generalized fixed dystonia that was refractory to bilateral pallidotomy and intrathecal baclofen therapy received 4 DBS leads, 2 through the bilateral superior cerebellar peduncle (SCP) and 2 in the dentate nuclei (DN). …
SUMMARY: A 91-year-old man with essential tremor was offered all available treatment modalities and opted for a radiofrequency thalamotomy. A left thalamic target with coordinates 11.5 mm lateral to the wall of the third ventricle, 8 mm anterior to the …
SUMMARY: Eleven patients underwent unilateral pallidothalamic tractotomy, including 5 with generalized dystonia, 4 with segmental dystonia, and 2 with cervical dystonia. All patients had undergone unilateral pallidotomy before the contralateral pallidothalamic tractotomy. The mean interval between the previous surgery (pallidotomy) …
SUMMARY: a patient with Wilson’s disease whose major problems were severe arm tremors and left arm dystonia underwent bilateral PSA-DBS with excellent results on both tremor and dystonia at 3 years follow up. COMMENTS: Another indication for use of the …