SUMMARY: Gamma ventral capsulotomy (GVC) in 21 patients with OCD. Mean follow-up 60.7 months. YBOCS 35.7 decreased to 15.3 at 36 months follow-up. 15 patients (75%) achieved a full response. Of those patients, 7 (35%) were considered to be in …
SUMMARY: More than 80 OCD DBS patients since 2005: guiding principles for optimizing DBS stimulation parameters in OCD. Adjustments in stimulation parameters are performed in a fixed order. First, electrode contact activation is determined by the position of the electrodes …
SUMMARY:21 patients with PD submitted to STN DBS compared with 19 eligible surgery candidates. Clinical measures included Hoehn and Yahr scale, UPDRS III, PDQ39, Becks Depressive inventory, and sexual function evaluation (Female Sexual Function Index and International Index of Erectile …
SUMMARY: Double-blind, sham-controlled, randomized multicenter (23 centers) trial STN DBS using BSc electrodes. 160 Patients were randomly assigned to receive either active therapeutic stimulation settings (active group) or subtherapeutic stimulation settings (control group) for the 3-month blinded period. The primary …
SUMMARY: To assess the prevalence and the cumulative incidence of dementia at short-, medium- and long-term (1, 5, and 10 years) follow-up after STN DBS and to evaluate potential risk factors for postoperative dementia. A total of 175 patients were …
SUMMARY: Beta-based adaptive Deep Brain Stimulation (aDBS) is effective in Parkinson’s disease (PD), when assessed in the immediate post-implantation phase. However, the potential benefits of aDBS in patients with electrodes chronically implanted, in whom changes due to the microlesion effect …
SUMMARY: The authors assessed the effects of different temporal patterns of cycling stimulation of posterior subthalamic area, subthalamic nucleus and the ventral intermediate nucleus of the thalamus in three PD patients with early decline of tremor suppression associated with severe …
SUMMARY: Recent developments in DBS lead and implantable pulse generator design provide increased flexibility for programming, potentially improving the therapeutic benefit of stimulation. Directional DBS leads may increase the therapeutic window of stimulation by providing a means of avoiding current …
SUMMARY: To compare clinical outcomes and DBS programming at 4 years between VIM and cZI DBS in ET-DBS patients, a retrospective review of 53 DBS leads from 47 patients was performed. Although improvement was still significant at 4 years, scores …
SUMMARY: The aim was to examine the long-term effects of STN-DBS in PD and evaluate the effect of reprogramming after more than 8 years of treatment. Methods: A total of 82 patients underwent surgery in Copenhagen between 2001 and 2008. …