SUMMARY: To compare nonmotor effects of STN-DBS and GPi-DBS. Observational, multicenter study including 60 PD patients undergoing bilateral STN-DBS (40) or GPi-DBS (20) were compared using PDQ 39, NMSS), UPDRS, Hoehn&Yahr, Schwab&England Scale, and levodopa-equivalent daily dose (LEDD) preop and …
SUMMARY: The benefit of short pulse width DBS in ET patients remains controversial. We report the effect of this type of stimulation in 3 patients with a persistent and severe intention tremor component despite iterative DBS setting adjustments. While a …
SUMMARY: Prospective, randomized trial to assess the motor outcomes of asleep DBS. Leads were implanted in the subthalamic nucleus (STN) according to probabilistic stereotactic coordinates with a surgical robot under O-arm imaging guidance under either general anesthesia without microelectrode recordings …
SUMMARY: Despite being introduced in clinical practice more than 20 years ago, selection criteria for deep brain stimulation (DBS) in Parkinson’s disease (PD) rely on a document published in 1999 called ‘Core Assessment Program for Surgical Interventional Therapies in Parkinson’s …
Management of Advanced Therapies in Parkinson’s Disease Patients in times of Humanitarian crisis: the COVID-19 experience. Fasano A, Antonini A, Katzenschlager R, Krack P, Odin P, Evans AH, Foltynie T, Volkmann J, Merello M. Mov Disord Clin Pract. 2020 May …
The reliability of Deep Brain Stimulation YouTube videos. Tripathi S, ReFaey K, Stein R, Calhoun BJ, Despart AN, Brantley MC, Grewal SS, Quinones-Hinojosa A, Wharen RE. J Clin Neurosci. 2020 Apr;74:202-204. SUMMARY: Patients are increasingly turning to the internet for …
Inhaled levodopa in Parkinson’s disease patients with OFF periods: A randomized 12-month pulmonary safety study. Grosset DG, Dhall R, Gurevich T, Kassubek J, Poewe WH, Rascol O, Rudzinska M, Cormier J, Sedkov A, Oh C. Parkinsonism Relat Disord. 2020 Feb;71:4-10. …
Could implanted medical devices be hacked? Jo Best. BMJ 2020;368:m102 SUMMARY: Jo Best is a freelance writer writing for the BMJ: She quotes Bill Aerts, executive director of the University of Michigan’s Archimedes Center for Medical Device Security saying:“Many implantable …
Impact of blinding on estimated treatment effects in randomised clinical trials: meta-epidemiological study. Moustgaard H, Clayton GL, Jones HE, Boutron I, Jørgensen L, Laursen DRT, Olsen MF, Paludan-Müller A, Ravaud P, Savović J, Sterne JAC, Higgins JPT, Hróbjartsson A. BMJ. …
Antibiotic exposure and risk of Parkinson’s disease in Finland: A nationwide case-control study. Mertsalmi TH, Pekkonen E, Scheperjans F. Mov Disord. 2020 Mar;35(3):431-442. SUMMARY: The authors evaluated the impact of antibiotic exposure on the risk of PD in a nationwide, …